ADMET

In the long process of drug development, early in vitro ADMET (absorption, distribution, metabolism - excretion and toxicity) is a crucial step for choosing the lead compounds that will have the desirable profiles (metabolism & safety) to provide a successful drug.  The ADMET properties, also known as DMPK (Drug Metabolism and Pharmacokinetics) will guide the scientists in their understanding of the drug’s safety and efficacy. These data also represent the base for future regulatory approvals.  

Based on our up-to-date knowledge of current legislation, regulatory requirements and international guidelines concerning drug R&D, CIDP PRECLINICAL will be your premium partner with a wide offer of comprehensive in vitro tests for absorption, distribution, metabolism and excretion (ADME) and toxicology evaluation of your drug candidate. Our preclinical team of experts can assist you in designing the validation stage of your product.
 

  • In Vitro Metabolism
     
  • In Vitro Permeability and Transporters
     
  • Polymorphic and Non-CYP Mediated Metabolism
     
  • Protein Binding
     
  • Bioanalysis