Established in 2004, CIDP (Centre International de Développement Pharmaceutique) is an international Contract Research Organisation (CRO) that carries out high R&D activities for pharmaceutical, medical device, nutraceutical and cosmetic industries.
PHOTOBIOLOGY STUDIES
With over 12 years of experience, trained experts in photobiology studies and a state of art equipment bank, CIDP Romania offers a wide range of in vivo as well as in vitro tests that are performed in accordance with the latest guidelines by:
- Cosmetics Europe (formerly COLIPA),
- International Standards (ISO guidelines)
- Food and Drug Administration (FDA) guidelines.
SUN PROTECTION FACTOR
With greater consumer awareness and regulations governing products claiming SPF (Sun Protection Factor), tanning, water-resistance, and skin lightening properties, CIDP assist its clients in providing robust data to regulatory authorities.
The SPF Calculation to determine the level of UV or UVB + UVA protection of a product can be done as per standard regional guidelines such as:
- FDA - Food and Drug Administration (United States)
- ISO 24444 - Cosmetics-Sun Protection Test Methods-In-Vivo Determination of the Sun Protection Factor (SPF)
- COLIPA Guidelines on International Sun Protection Factor (COLIPA, CTFA SA, JCIA and CRFA) May 2006
UVA PROTECTION STUDIES
Calculation of the UVA-PF (time-induced pigment response) of a product conducted under the:
- JCIA Method (PA, PFA, PPD)
- ISO 24442 – Cosmetics-Sun Protection Test Methods-In-Vivo Determination of Sunscreen UVA Protection
- Combine method following the standards UVA ISO 24442 & JCIA
Assessment of Spectral Photostability
Assessment of Spectral Photostability (single UV dose), in vitro UVA Protection Factor and Critical Wavelength of a sunscreen
The adopted method provides an accurate in vitro evaluation of the UVA PF of cosmetic products, is based on the assessment of UV-transmittance through a thin film of sunscreen sample spread on a roughened substrate, before and after exposure to a controlled dose of radiation from a defined UV exposure dose. Samples are then exposed to a specific measured dose of UV radiation to account for the photostability characteristics of the test product.
Conducted under the:
- ISO 24443 – Determination of sunscreen UVA photo-protection in vitro
- COLIPA 2011
WATER RESISTANT TESTING
The Water-resistant properties and SPF calculation to determine the level of protection offered by product post-water immersion can be conducted according to FDA – Food and Drug Administration (United States).
METHODOLOGIES
Methodology 1: Combine method following the standards ISO/EN 24444 Cosmetics-Sun protection test methods-in vivo determination of the Sun Protection Factor (SPF) (2010) and COLIPA Guidelines for Evaluating Sun product Water resistance (Dec 2005)
Methodology 2: Combine method following the standards ISO/EN 24444 Cosmetics-Sun protection test methods-in vivo determination of the Sun Protection Factor (SPF)(2019) and ISO 16217:2020 Cosmetics — Sun protection test methods — Water immersion procedure for determining water resistance, ISO 18861:2020 Cosmetics — Sun protection test methods — Percentage of water resistance. The methodology used is same as described above.
STRESS CLAIM STUDIES
Variants of the SPF ISO 24444 method in which the objective is to evaluate the different stress resistance of the tested products, by comparing its SPF obtained by normal application to the SPF obtained after stress is applied.
Friction Resistance
The objective is to evaluate the friction resistance of the tested product, by comparing its SPF obtained by normal application to the SPF obtained after friction (performed by insisting with double moves for the application method).
Rubbing Resistance
The objective is to evaluate the rubbing resistance of the tested product, by comparing its SPF obtained by normal application to the SPF obtained after rubbing of the zone on a towel.
Sand Resistance
The objective is to evaluate the sand resistance of the tested product, by comparing its SPF obtained by normal application to the SPF obtained after sand application and removal on the tested zone
Persistence
The objective is to evaluate the persistence of the tested product, by comparing its SPF obtained by exposure of the tested zone after 15-30 minutes after the application, to the SPF obtained after exposure done after 4, 6 or 8 hours after the product application (or other time span desired).
Sweat Resistance
The objective is to evaluate the sweat resistance of the tested product, by comparing its SPF obtained by normal application and exposure to the SPF obtained after profuse sweating of the tested site (sweating is achieved by subjects running on a treadmill).
CIDP is an active member of the AFNOR Standardization Committee
AFNOR/S91KGT07 -“Produits de protection solaire“
AFNOR/S91K -“Produits Cosmétiques“
+1200SPF studies
+450Water Resistant
+500UVA Studies
+40Phototox Studies